FAK anticorps (Middle Region)

N° du produit ABIN2791666

Cet anticorps anti-FAK est un anticorps Lapin Polyclonal détectant FAK dans WB. Adapté pour Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Lapin, Boeuf (Vache), Cheval et Cobaye.

Aperçu rapide pour FAK anticorps (Middle Region) (ABIN2791666)

Antigène: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Lapin, Boeuf (Vache), Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FAK anticorps

Épitope: Middle Region

Séquence: SEKQGMRTHA VSVSETDDYA EIIDEEDTYT MPSTRDYEIQ RER
IELGRC

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PTK2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of Human PTK2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur FAK

Antigène: FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Autre désignation: PTK2

Sujet: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined.
Protein Interaction Partner: DEF6, SOCS3, YES1, IQGAP1, UBE2H, UBC, TRIM72, SRPK1, PXN, PTRH2, SAE1, HSP90AA1, APP, RBSN, BCAR1, KCNJ3, PTAFR, STAT1, CBL, STAP2, STUB1, PTPN11, PPP1CB, PPP1CA, SRC, CTTN, ASAP1, SH3KBP1, PDCD6IP, ITGB5, ELAVL1, DAG1, GRB2, FBP1, F13A1, EEF1G, LPXN, TG
Protein Size: 431

Poids moléculaire: 47 kDa

ID gène: 5747

Pathways: Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling